A best actor nominee for 2003′s “Lost in Translation,” Murray could have Oscar prospects again as Franklin Delano Roosevelt in “Hyde Park on the Hudson,” a comic drama that played the ongoing Toronto International Film Festival.

Murray won a string of key prizes for “Lost in Translation” leading up to the Oscars, including a Golden Globe, an Independent Spirit Award and honors from many critics groups.

Murray is a rare comic actor who has evolved into a performer with the depth to create characters that put him into the awards mix with such films as Rushmore, ”Get Low and Broken Flowers.

The former Saturday Night Live regular and crazy man of Ghostbusters, ”Caddyshack and Stripes first dabbled in heavy drama with a 1984 adaptation of W. Somerset Maugham’s The Razor’s Edge.

After The Razor’s Edge, ”I remember a certain famous movie reviewer saying, ‘Bill Murray should not be allowed to do anything but comedy,’ which I reminded him of at the Cannes Film Festival when I was nominated for an Oscar, Murray said.

Murray’s sister had polio, the disease that crippled Roosevelt, so the actor said he had a strong sense of how to play the president’s body language as he struggles on crutches, is pushed about in a wheelchair or is curled like a child in the arms of aides who lift him in and out of cars.

Murray worked with a voice coach to break down the unusual mix of vowel sounds in Roosevelt’s speech.